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Updated: Jun 3, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

独創的なアーキテクチャを持つシステニル・リンクド・ヌクレオチド・アナログを自律的にペアリングする

Manuel Peifer1, Andrea Vasella

  • 1Laboratory for Organic Chemistry, ETH Zürich, CH-8093 Zürich, Switzerland.

Journal of the American Chemical Society
|March 10, 2011
PubMed
まとめ

研究者らは新しいオリゴヌクレオチドアナログを作り,水で効率的にペア化し,安定したダブルヘリックスを形成しました. この画期的な発見は,核酸の構造に関する伝統的な見解に異議を唱え,分子設計の新たな可能性を提供します.

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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

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