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Updated: Jun 23, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

化学免疫グロブリンT細胞受容体タンパク質は,機能的受容体を形成する:T細胞受容体複合体の形成と活性化への影響

J Goverman1, S M Gomez, K D Segesman

  • 1Division of Biology, California Institute of Technology, Pasadena 91125.

Cell
|March 23, 1990
PubMed
まとめ

研究者は,免疫グロブリン変数領域を使用して,キメリックT細胞受容体 (Tcr) チェーンを作成しました. これらの機能的なTcr複合体はCD3と結合し,特定の抗原に反応し,アルファ定数領域がTcr複合体の形成に不可欠ではないことを示している.

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In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

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