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Updated: Jun 3, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

タンパク質結合ペプチドの配列と構造の計算設計

Deanne W Sammond1, Dustin E Bosch, Glenn L Butterfoss

  • 1Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599-7260, USA.

Journal of the American Chemical Society
|March 11, 2011
PubMed
まとめ

新しいタンパク質結合ペプチドを設計することは困難です. 研究者は,Gα(i1) タンパク質に結合するペプチドを計算的に再設計し,X線結晶学で検証された新しい形状を達成しました.

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