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Updated: Jun 3, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

植物型IIIポリケチド合成酵素によって生成された細胞毒性テトラミック酸派生体

Toshiyuki Wakimoto1, Takahiro Mori, Hiroyuki Morita

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|March 12, 2011
PubMed
まとめ

研究者らは,植物特異のベンザラセトン合成酵素 (BAS) を使用して,新しいテトラミック酸誘導体を設計した. 1つの誘導体は適度な抗増殖活性を示し,この多用途酵素の潜在能力を拡大しました.

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