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Updated: Jun 3, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

簡潔な合成とセスクイテルペンの類似体の構造的多様化を通じて,抗トライパノソーム剤の生成

Hiroki Oguri1, Takahisa Hiruma, Yutaka Yamagishi

  • 1Division of Chemistry, Graduate School of Science, Creative Research Institution, Hokkaido University, North 21, West 10, Sapporo 001-0021, Japan. oguri@sci.hokudai.ac.jp

Journal of the American Chemical Society
|March 19, 2011
PubMed
まとめ

研究者らは,ヒトのアフリカトライパノソミアシスのような見捨てられた病気と闘うために,新しい合成サイクリック・スカファッドを開発しました. これらのアルテミシニンにインスパイアされた化合物は,強力な抗トリパノソーム活性を示し,新しい治療法を提供しています.

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