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3D Modeling of Dendritic Spines with Synaptic Plasticity
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単一 dendritic スパインの可塑性中にRho GTPasesの局所的で持続的な活性化

Hideji Murakoshi1, Hong Wang, Ryohei Yasuda

  • 1Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.

Nature
|March 23, 2011
PubMed
まとめ

RhoAとCdc42のGTPアゼは,神経 dendritic spinesの構造的な可塑性にとって決定的に重要です. 彼らの独特の活性化パターンと経路は,CaMKIIによって調節され,長期的なシナプス変化を可能にします.

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