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Updated: Jun 29, 2026

Step-specific Sorting of Mouse Spermatids by Flow Cytometry
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培養された新生児マウスの testiclesで機能性精子のインビトロ生産

Takuya Sato1, Kumiko Katagiri, Ayako Gohbara

  • 1Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Nature
|March 25, 2011
PubMed
まとめ

科学者たちはマウスの丸でインビトロ精子生成を成功裏に達成し,子孫のために生存可能な精子を生産しました. 生殖生物学におけるこの画期的な発見は,生殖研究と潜在的な臨床応用のための新しい道を開く.

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関連する概念動画

Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Spermatogenesis01:22

Spermatogenesis

Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...