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Updated: Jun 3, 2026

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HMGB1によって認識された曲げられたDNAの構造的特徴

Kyoko Furuita1, Shunpei Murata, Jun Goo Jee

  • 1Laboratory of Biophysics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan.

Journal of the American Chemical Society
|March 30, 2011
PubMed
まとめ

HMGB1 (High Mobility Group Box 1) タンパク質は,曲ったDNAに特異的に結合する. 小さい溝のポケット構造は,HMGB1の強い結合に不可欠であり,フェニララニン残基の浸透を可能にします.

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