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Updated: Jun 3, 2026

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination
07:58

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination

Published on: January 2, 2026

線形ユビキチネーションは炎症を予防し,免疫信号を調節する

Björn Gerlach1, Stefanie M Cordier, Anna C Schmukle

  • 1Tumour Immunology Unit, Department of Medicine, Imperial College London, W12 0NN London, UK.

Nature
|April 2, 2011
PubMed
まとめ

SHARPINは,免疫信号伝達における重要なタンパク質として特定されています. TNF誘発の細胞死と炎症を,線形ユビキチネーションを in vivo 調節することによって防ぐ.

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