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Updated: Mar 31, 2026

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
08:15

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

Published on: April 11, 2025

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NEMOとRIP1は,TNF-αのフィードフォワードシグナル伝達を通じて,広範なDNA損傷に対する反応として,細胞運命を制御する

Sharon Biton1, Avi Ashkenazi

  • 1Department of Molecular Oncology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

Cell
|April 5, 2011
PubMed
まとめ

アタクシア・テランジエクタジア・ミューテッド (ATM) キナーゼは,DNA損傷後のサイトカインの放出とアポトーシスをシグナルする. この研究では,細胞運命を決定する上で極めて重要なNF-κBとRIP1キナーゼを含むp53独立経路が明らかになりました.

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Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO

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Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA06:46

Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA

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No description available
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