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Updated: May 5, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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Bcl-x(L) は,ミトコンドリアからBaxを細胞溶液に逆転移する

Frank Edlich1, Soojay Banerjee, Motoshi Suzuki

  • 1Surgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|April 5, 2011
PubMed
まとめ

Prosurvival Bcl-2タンパク質は,Bcl-x(Lのように,バックスをミトコンドリアから細胞溶液に絶えず戻すことによって,アポトーシスを抑制します. このレトロトランスロケーションメカニズムは,バックスを不活性な細胞細胞状態に維持します.

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