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Updated: Jun 3, 2026

Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
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estreptococcal M1のタンパク質は,病的な宿主である線維原素ネットワークを構築する

Pauline Macheboeuf1, Cosmo Buffalo, Chi-yu Fu

  • 1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA.

Nature
|April 9, 2011
PubMed
まとめ

ストレプトコックスのM1タンパク質はフィブリノゲンとユニークな複合体を形成し,中性粒子を活性化し,毒性ショックのような症状を引き起こします. この構造を理解することで,細菌がどのようにして重度の組織損傷を引き起こすのかが明らかになる.

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