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関連する概念動画

MicroRNAs01:22

MicroRNAs

24.2K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
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piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

7.6K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.6K

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関連する実験動画

Updated: Jan 29, 2026

Delivery of Exogenous Artificially Synthesized miRNA Mimic to the Kidney Using Polyethylenimine Nanoparticles in Several Kidney Disease Mouse Models
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アルゴナウト10はmiRNAロッカーとして使用されています.

Pablo A Manavella1, Detlef Weigel, Liang Wu

  • 1Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

Cell
|April 19, 2011
PubMed
まとめ

植物では,アルゴナウトタンパク質を使用して,マイクロRNA (miRNA) を封鎖し,メッセンジャーRNAの安定性と翻訳を調節するのを防ぐ. この研究は,miRNA-Argonaute結合を含む植物における新しい規制メカニズムを明らかにしています.

科学分野:

  • 分子生物学は分子生物学である.
  • 植物科学 植物科学について
  • 遺伝子規制 遺伝子規制

背景:

  • マイクロRNA (miRNA) は遺伝子発現の重要な調節体であり,メッセンジャーRNA (mRNA) の安定性と翻訳効率に影響を与えます.
  • アルゴナウト (AGO) タンパク質は,RNA誘発サイレンシング複合体 (RISC) の重要な構成要素であり,miRNAの機能を媒介する.
  • miRNA媒介の遺伝子調節を理解することは,植物の発達とストレス反応にとって極めて重要です.

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Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats
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関連する実験動画

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mirMachine: A One-Stop Shop for Plant miRNA Annotation
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