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Updated: Jun 2, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
11:07

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding

Published on: September 21, 2011

広範囲にわたる否定的な応答要素は,アゴニスト・リガンドド・グルココルチコイド受容体による直接抑制を媒介する.

Milan Surjit1, Krishna Priya Ganti, Atish Mukherji

  • 1Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, Inserm U964, Université de Strasbourg, Collège de France, Illkirch, 67404, France.

Cell
|April 19, 2011
PubMed
まとめ

グルココルチコイド受容体 (GR) は,以前に知られているメカニズムとは独立して,新しいDNA配列 (IR nGREs) に結合することによって,遺伝子を直接抑制します. この直接的な抑制は,変動するグルココルチコイドレベルによって,新しい層の遺伝子調節を提供します.

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Inducible, Cell Type-Specific Expression in Arabidopsis thaliana Through LhGR-Mediated Trans-Activation09:31

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