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Updated: Jun 2, 2026

Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae
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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae

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DNA合成は端末複製を生成し,エンドツーエンドの染色体融合をシールする

Mia Rochelle Lowden1, Stephane Flibotte, Donald G Moerman

  • 1Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|April 23, 2011
PubMed
まとめ

ゲノム複製が染色体融合を封じ込めることは,単に断裂-融合-橋渡しサイクルではなく,DNA合成から生じる可能性があります. この研究では,テロメア変異体におけるエンドツーエンドの融合を調査し,複製中のテンプレートスイッチングを明らかにしています.

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