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Updated: Jun 2, 2026

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy (TIRFM)
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"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy (TIRFM)

Published on: August 26, 2016

"ファゴサイトシナプス"の形成時に生まれながらの免疫受容体Dectin-1の活性化

Helen S Goodridge1, Christopher N Reyes, Courtney A Becker

  • 1IBD and Immunobiology Research Institute, 8700 Beverly Boulevard, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

Nature
|April 29, 2011
PubMed
まとめ

生まれながらの免疫細胞はDectin-1を使用して真菌を検出します. この研究では,Dectin-1のシグナル伝達は,溶解性β-グルカンではなく,粒子状β-グルカンによってのみ活性化され,偽の免疫反応を防ぐことが明らかになりました.

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