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Updated: Jun 2, 2026

Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment
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異常な脂質代謝は,カルシウムホメオスタシスを乱し,肥満における肝臓内プラズマ網膜のストレスを引き起こします

Suneng Fu1, Ling Yang, Ping Li

  • 1Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

Nature
|May 3, 2011
PubMed
まとめ

肥満は,肝細胞の脂質代謝を変化させ,カルシウム処理とインスリン感受性を損なうことで慢性的なエンドプラズマ網膜 (ER) ストレスを引き起こす. 脂質バランスを回復したり,SERCA機能を強化したりすることで,このストレスが軽減され,グルコースコントロールが改善されます.

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