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Updated: Jun 2, 2026

Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis
10:03

Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

Published on: July 16, 2008

ヒトプリオンタンパク質の集積のための多段階の経路 in vitro: マルチメリックシードからβ-オリゴーマー,非線維構造まで

Kang R Cho1, Yu Huang, Shuiliang Yu

  • 1Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA.

Journal of the American Chemical Society
|May 4, 2011
PubMed
まとめ

クルーツフェルト・ヤコブ病 (CJD) の特徴である異常なタンパク質集積が研究されました. 研究者らは,タンパク質の集積は,単一のタンパク質を添加することによって形成されるのではなく,より小さなβ-オリゴマーの結合によって形成されることを発見しました.

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Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster

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Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain11:29

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain

Published on: October 3, 2012

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Amyloid Fibrils03:03

Amyloid Fibrils

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Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid Fibrils03:03

Amyloid Fibrils

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Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...
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Protein Folding01:22

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Overview