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Updated: Jun 2, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

細胞浸透性オリゴヌクレオチド-オリゴスペルミン結合体による遺伝子発現のアンチセンセと抗原阻害

Keith T Gagnon1, Jonathan K Watts, Hannah M Pendergraff

  • 1Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Journal of the American Chemical Society
|May 5, 2011
PubMed
まとめ

Zip核酸 (ZNA) は,新しいオリゴヌクレオチド-オリゴスペルミン結合体であり,細胞伝達における課題を克服します. これらのZNAは,低濃度でアンチセンセと抗原剤として,遺伝子発現を効果的に沈黙させます.

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In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge

Published on: June 15, 2018

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