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Updated: Mar 18, 2026

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

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酵素触媒による [4+2] サイクル添加は,スピノシンAの生物合成の重要なステップです

Hak Joong Kim1, Mark W Ruszczycky, Sei-hyun Choi

  • 1Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA.

Nature
|May 6, 2011
PubMed
まとめ

研究者らは,スピノシンA生物合成におけるディエルス・アルダー反応を触媒する最初の専用酵素であるSpnFを特定した. この酵素は,特にサイクロヘキセンの環形成を加速し,天然製品合成の重要なステップを明確にします.

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