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Updated: Jun 2, 2026

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates
06:48

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates

Published on: January 5, 2024

HIV-1プロテアゼのダイナミクスに関する洞察:原子学的シミュレーションから構築された運動ネットワークモデル

Nan-jie Deng1, Weihua Zheng, Emillio Gallicchio

  • 1BioMaPS Institute for Quantitative Biology and Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854, USA.

Journal of the American Chemical Society
|May 13, 2011
PubMed
まとめ

この研究は,原子学的シミュレーションと移行経路理論を使用して,HIV-1プロテアースフラップのダイナミクスをモデル化しています. 薬の開発に不可欠な基質結合の温度に依存する経路を明らかにしています.

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