エストロゲン受容体は脳炎症をトランスプレッシャーします
1Laboratory of Endocrinology and Genomics, CHUQ Research Center and Department of Molecular Medicine, Faculty of Medicine, Laval University, 2705 Laurier Boulevard, Québec, G1V 4G2, Canada.
Cell
|May 14, 2011
まとめ
エストロゲン受容体β (ERβ) は多発性硬化症において重要な役割を果たします. この経路は,炎症を抑制し,マウスモデルでの疾患の進行を遅らせ,新しい治療標的を提供します.
科学分野:
- 神経免疫学 神経免疫学とは
- エンドクリノロジー エンドクリノロジー
背景:
- エストロゲン受容体 (ERs) は,多発性硬化症 (MS) の病因と関連しています.
- ERとMSの病理を結びつける正確な分子機構は不明である.
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