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Updated: Jun 1, 2026

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
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Pb2+はタンパク質と膜の相互作用の調節剤として作用する

Krystal A Morales1, Mauricio Lasagna, Alexey V Gribenko

  • 1Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA.

Journal of the American Chemical Society
|May 28, 2011
PubMed
まとめ

鉛 (Pb2+) は,タンパク質キナーゼCα (PKCα) のC2α領域に結合し,カルシウム (Ca2+) よりも高い親和性を有し,その膜結合に影響を与え,鉛の毒性につながる可能性があります.

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