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Updated: Jun 1, 2026

Microfluidic Mixers for Studying Protein Folding
12:42

Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

タンパク質の折りたたみに対するチャペロニン効果のシミュレーション:核形成-凝縮からフレームワークメカニズムへの移行

Sebastian Kmiecik1, Andrzej Kolinski

  • 1Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland. sekmi@chem.uw.edu.pl

Journal of the American Chemical Society
|May 31, 2011
PubMed
まとめ

チャペロニンは,誤った折り畳みを防止し,折り畳み経路を変更することによって,タンパク質の折り畳みを加速します. この研究では,チャペロニンの作用をシミュレートするために粗粒線モデルを使用し,タンパク質の動態と折り畳み温度への影響を明らかにしました.

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