早期再偏極化:長期的に有利な結果と関連した心電図現象
Jani T Tikkanen1, M Juhani Junttila, Olli Anttonen
1Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Oulu, Finland. jani.tikkanen@oulu.fi
Circulation
|June 3, 2011
まとめ
ECGの早期再極化 (ER) は心律不良による死亡リスクを高めます. しかし,ER後の特定のSTセグメントパターンは,アスリートに共通する上昇型のように,良性変異を示し,このリスクを高めることはありません.
科学分野:
- 心臓病学 心臓病学
- エレクトロカーディオグラフィーです.
- 心臓発作による突然死.
背景:
- 下部/側部EKG導線における早期再極化 (ER) は,突然の不律性死のリスクの増加と関連しています.
- ER波形によるSTセグメントの特徴の変動は,予後的な意味を持つ可能性があります.
研究 の 目的:
- 電気心臓図 (ECG) の早期再極化 (ER) 後のSTセグメント変異の予後的重要性を調査する.
- ERに関連した特定のSTセグメント形態が,不律性死亡のリスクが増加した個人とそれ以外の個人を区別できるかどうかを判断する.
主な方法:
- 若いアスリート (フィンランド,n=62;米国,n=503) のEKGを分析し,ER後のSTセグメントの形態を特徴づけました.
- 一般的な中年集団 (n=10,864) のECGの評価により,ERに関連したSTセグメントの変異が不律性死亡リスクに与える予後効果を評価した.
主要な成果:
- アッセンディング/アップスロップST変種は,アスリートにおけるERの支配的な形態であった (96%のフィンランド人,85%の米国人).
- 一般人群では,水平/下降のST変種 (n=412) を含むERでは,不律性死亡のリスク比率が増加した (RR1.43).
- 横行/下行ST変異によるより高い振幅のER (>0.2mV) は,不律性死のリスク比率 (RR3.14) を有意に増加させたが,上行ST変異はリスク増加を示さなかった (RR0.89).
結論:
- ERに関連したSTセグメントの形態の変化は,中年個人の不律性死亡リスクの階層化において重要である.
- 健康なアスリートに多く見られる,急速に上昇するSTセグメントパターンは,ERの良性多様体であるようです.
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