12導電心電図における早期再偏極化パターンの発生率と予後値
Daisuke Haruta1, Kiyotaka Matsuo, Akira Tsuneto
1Department of Clinical Studies, Radiation Effects Research Foundation, 1-8-6 Nakagawa, Nagasaki, Japan. harutad@rerf.or.jp
Circulation
|June 8, 2011
まとめ
ECGの早期再極化パターン (ERP) は,アジア人群に共通しています. 心臓発作および全原因死亡の減少と関連しているが,ERPは予期せぬ死亡のリスクが高いことを示している.
科学分野:
- 心臓病学 心臓病学
- エレクトロカーディオグラフィーです.
- 公衆衛生は公衆衛生である.
背景:
- 早期再極化パターン (ERP) は,心電図 (ECG) でよく見られる結果です.
- Jポイントの上昇とQRSのノッチング/スラージングが下部/側面のリードで特徴です.
- アジアの集団におけるERPの発生率と予後に関するデータは限られている.
研究 の 目的:
- アジアの集団におけるERPの発生率と長期的な予後を調べる.
- ERPと予期せぬ,心臓,およびあらゆる原因による死亡のリスクとの関連性を評価する.
主な方法:
- 日本,長崎 (1958年-2004年) の原爆の生存者5976人のECG記録の遡及分析.
- ERPは,≥0.1-mVのJポイント/ST高さで,≥2の下部/横部導線にノッチング/スラージングがあるとして定義されています.
- 様々な死亡タイプのリスクを評価するためにコックス分析を使用しました.
主要な成果:
- 1429件のERP症例 (23.9%の流行率) が特定され,発生率は10万人当たり715例であった.
- ERPは予期せぬ死亡リスクの増加 (HR 1.83) と関連していたが,心臓病 (HR 0.75) と全死因死亡リスクの減少 (HR 0.85) と関連していた.
- 特定の形状 (スラージング/ノッチング) および位置 (下部および横部リード) は,予期せぬ死亡のリスクが高いと相関しています.
結論:
- 早期の再偏極化パターンは,予期せぬ死のリスクの高さに関連しています.
- ERPは,心臓病およびあらゆる原因による死亡リスクの低下を示しています.
- ERPの特定の特徴は,より悪い予後を予測し,さらなる調査の必要性を強調しています.
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