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Updated: May 5, 2026

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins

Published on: September 28, 2012

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ヒトがんにおけるタンパク質インタラクトーム解析によって発見されたDNA修復におけるサイクリンD1の機能

Siwanon Jirawatnotai1, Yiduo Hu, Wojciech Michowski

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.

Nature
|June 10, 2011
PubMed
まとめ

細胞サイクルタンパク質であるサイクリンD1は,損傷部位にRAD51を結合することによって,意外とDNA修復を助けます. サイクリンD1を阻害することで,網膜芽細胞腫陰性がんの治療が可能になり,治療の可能性が広がります.

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