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Updated: Jun 1, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
10:37

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

タンパク質調節された上流のオープン・リーディング・フレームによる翻訳制御

Jan Medenbach1, Markus Seiler, Matthias W Hentze

  • 1European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Cell
|June 14, 2011
PubMed
まとめ

セックス・レタル (SXL) タンパク質は,mRNAのアップストリームオープン・リーディングフレーム (uORF) 経由で翻訳を調節する. uORFの近くのSXL結合は,翻訳開始を制御することによって,タンパク質合成を阻害する.

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