非筋肉のミオシン・ライトチェーンキナーゼ欠乏症は,減少した内皮壁機能障害と単細胞移動経由で,アポリポプロテインE欠乏性マウスの動脈硬化を弱める

Chongxiu Sun1, Mack H Wu, Sarah Y Yuan

  • 1Department of Surgery, University of California Davis School of Medicine, 4625 2nd Ave, Room 3005, Sacramento, CA 95817, USA.

Circulation
|June 15, 2011
PubMed
まとめ

非筋肉のミオシン軽鎖キナーゼ (nmMLCK) 欠乏症は,内皮壁機能を改善し,単細胞の移動を減少させることで,動脈硬化症の発症を減少させます. これはキナーゼ活動とSrcシグナル伝達経路の両方を含む.

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