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Updated: Jan 10, 2026

Nephrotic Syndrome I : Introduction
01:24

Nephrotic Syndrome I : Introduction

Published on: June 19, 2025

476

分泌タンパク質ペプシノゲンでリゾソーム酵素ターゲティング信号を生成する

T J Baranski1, P L Faust, S Kornfeld

  • 1Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.

Cell
|October 19, 1990
PubMed
まとめ

研究者らは,マノース6リン酸形成に不可欠なリゾソーム酵素の特定のタンパク質決定因子を特定しました. カテプシンDの2つの連続しない配列によって形成されるこの決定因子は,酵素ターゲティングとリン酸化に不可欠です.

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Nephrotic Syndrome I : Introduction01:24

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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