関連する実験動画

Updated: May 31, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

X不活性化のためのYY1ブリッジ

Joanne L Thorvaldsen1, Jamie R Weaver, Marisa S Bartolomei

  • 1Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA.

Cell
|July 7, 2011
PubMed
まとめ

XistRNAは,X染色体と結合することで,X染色体を無活性化する. タンパク質YY1は,XistRNAをDNA結合によって不活性X染色体 (Xi) に結合させ,X染色体の不活性化を促進する.

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X-Inactivation01:58

X-Inactivation

The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
X-inactivation01:58

X-inactivation

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Inheritance of Chromatin Structures

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