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Updated: May 31, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
04:38

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions

Published on: July 28, 2022

1,2,3-トリアジンの逆電子需要ダイエルス・アルダー反応:反応性およびサイクル添加の範囲に対する顕著な置換物効果

Erin D Anderson1, Dale L Boger

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|July 9, 2011
PubMed
まとめ

この研究は,C5置換剤が1,2,3-トリアジンの逆電子需要ダイエルス・アルダー反応を著しく強化することを明らかにしています. この予測可能な調節により,合成用途と範囲がヘテロサイクリックアザディエンとして拡大する.

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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