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Updated: May 31, 2026

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases

Published on: October 10, 2020

専用のグルタチオンS-トランスフェラーゼは,グリオトキシン生物合成における炭素硫黄結合形成を媒介する

Daniel H Scharf1, Nicole Remme, Andreas Habel

  • 1Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstr. 11a, 07745 Jena, Germany.

Journal of the American Chemical Society
|July 14, 2011
PubMed
まとめ

この研究は,グルタチオンS-トランスフェラーゼ (GST) のGliGが,アスペルギルス・フミガトゥスの主要な毒素であるグリオトキシンに硫黄結合を生成する方法を示しています. この発見は,侵襲性アスペルギロシスの理解に極めて重要です.

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