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Updated: May 31, 2026

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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腫瘍低酸素症は,CCL28およびT ((reg) 細胞経由で耐性および血管新生を促進する

Andrea Facciabene1, Xiaohui Peng, Ian S Hagemann

  • 1Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Nature
|July 15, 2011
PubMed
まとめ

腫瘍低酸素症は,CCL28経由で調節性T細胞 (Treg) を募集することで免疫逃避を促進し,耐性および血管新生を促進します. この発見は,免疫的耐性と血管の成長を,持続的な腫瘍進行と関連付けています.

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