HIV予防の変革:新しい予防研究アジェンダ

Nancy S Padian¹, Sandra I McCoy, Salim S Abdool Karim

¹Division of Epidemiology, University of California, Berkeley, CA 94704, USA.

Lancet (London, England)

|July 19, 2011

まとめ

このレビューは,HIV予防の進展を調査し,HIVパンデミックに効果的に闘うために,人口レベルでの組み合わせ戦略の実施に焦点を当てています.

科学分野:

公衆衛生は公衆衛生である.
エピデミオロジーエピデミオロジー
感染症予防感染症予防

背景:

ヒト免疫不全ウイルス (HIV) 予防の焦点は,生物医学的な発見から,実施科学と人口レベルでの有効性を含むことに移行しました.
現在のHIV予防戦略の広範な適用には,重要な知識のギャップと実践的な課題が残っています.

研究の目的:

HIV予防の分野における現在の動向を分析する.
効果的かつ効率的な組み合わせによる予防戦略の実施を優先する将来の研究課題を提案する.
予防の努力を強化することによって,世界的なHIVパンデミックに対処するためのロードマップを提供すること.

主な方法:

HIV予防研究における最近の文献と動向の包括的なレビュー.
実施科学,有効性研究,および組合せ予防の集団レベルの影響の分析.
重要な研究優先事項を特定するために,発見の合成.

主要な成果:

HIV予防の風景は急速に変化しており,実用的な応用と人口レベルの影響がますます重視されています.
組み合わせ防止戦略は有望ですが,実施と効率性に関する集中的な研究が必要です.
予防の効果を最大化するために,既存の実施上の課題に対処する必要がある.

結論:

実施科学へのパラダイムシフトは,HIV予防の進歩に不可欠です.
将来の研究は,組み合わせた予防戦略の効果的かつ効率的な展開を優先しなければなりません.
実施のギャップを解決することは,HIVパンデミックを制御し,最終的に終結させるための鍵です.

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