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Updated: May 31, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

CD4結合を模倣する広範で強力なHIV抗体の配列と構造的収束

Johannes F Scheid1, Hugo Mouquet, Beatrix Ueberheide

  • 1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Science (New York, N.Y.)
|July 19, 2011
PubMed
まとめ

研究者らは,4人の個人に強力な,広範に中和するHIV抗体を特定しました. これらの抗体はCD4結合を模倣し,保存された遺伝的起源を共有し,HIV感染に対するワクチン開発のための新しい洞察を提供します.

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Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Antibodies consist of four polypeptide chains: two identical heavy...
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
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Antibodies, also known as immunoglobulins, are produced by B cells in response to foreign substances, such as bacteria and viruses. These proteins are critical for recognizing and neutralizing these substances, protecting the body from potential harm.
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