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Updated: May 31, 2026

Cell-Free Protein Synthesis System for Building Synthetic Cells
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サイアノバクテリアにおけるリボソームペプチドプレニレーションの酵素的基礎

John A McIntosh1, Mohamed S Donia, Satish K Nair

  • 1Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

Journal of the American Chemical Society
|July 20, 2011
PubMed
まとめ

研究者らは,サイアノバクチンと呼ばれる周期性ペプチドを改変するプロニルトランスフェラーゼ酵素であるLynFを特定した. この発見は,成熟したペプチドのプレニル化とクライゼン再編成機構を含む天然製品バイオシンセシスの新しい経路を明らかにしています.

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