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Updated: May 31, 2026

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

(E) -アルケンとエチレンイソステルは,MHC A(q) /グリコペプチド複合体のクラスIIの水素結合ネットワークを大幅に変化させ,T細胞の認識に影響を与えます

Ida E Andersson1, Tsvetelina Batsalova, Sabrina Haag

  • 1Department of Chemistry, Umeå University, SE-901 87 Umeå, Sweden.

Journal of the American Chemical Society
|July 20, 2011
PubMed
まとめ

抗原プレゼンテーションにおける水素結合の調査は,ペプチドの改変が,自己免疫疾患の研究に不可欠な,クラスIIメジャーヒストコンパティビリティ・コンプレックス (MHC) タンパク質への結合にどのように影響するかを明らかにしています.

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