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Updated: May 30, 2026

Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
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Published on: March 16, 2020

β2 アドレナゲン受容体-Gs タンパク質複合体の結晶構造

Søren G F Rasmussen1, Brian T DeVree, Yaozhong Zou

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|July 21, 2011
PubMed
まとめ

この研究では,活性Gタンパク質結合受容体 (GPCR) 複合体の最初の高解像度結晶構造が明らかになりました. ベータ-2アドレネルギー受容体 (β(2) AR) とそのGタンパク質であるGsとの相互作用を詳細に説明し,トランスメブラン信号伝達に関する洞察を提供します.

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