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Updated: May 30, 2026

Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

アフリカ系アメリカ人における再結合の風景

Anjali G Hinch1, Arti Tandon, Nick Patterson

  • 1Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK.

Nature
|July 22, 2011
PubMed
まとめ

遺伝子の再組み合わせによって,多様性が生まれます. 研究者は,アフリカ系アメリカ人におけるヒトのクロスオーバー率をマッピングし,PRDM9遺伝子と独特のDNAモチーフの影響を受けた集団特有の再結合ホットスポットを明らかにしました.

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Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae09:40

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae

Published on: September 23, 2011

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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In order to...
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Homologous Recombination

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