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FADDはRIP3媒介の上皮細胞死滅と慢性腸炎を予防する

Patrick-Simon Welz1, Andy Wullaert, Katerina Vlantis

  • 1Institute for Genetics, Centre for Molecular Medicine, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

Nature
|August 2, 2011
PubMed
まとめ

ファス関連死亡領域 (FADD) タンパク質は,腸内皮質細胞 (IEC) のプログラム性死滅を防ぐ. RIP3に依存したIECの死滅を阻害することで,腸壁の完全性を保ち,炎症性腸疾患を予防します.

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