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Updated: May 30, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
09:14

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

コルベ型デカルボキシル化の構造的基礎は,グリシル基素酵素によって触媒化された

Berta M Martins1, Martin Blaser, Mikolaj Feliks

  • 1Institute für Biologie, Strukturbiologie/Biochemie, Humboldt-Universität zu Berlin, D-10115 Berlin, Germany. berta.martins@biologie.hu-berlin.de

Journal of the American Chemical Society
|August 10, 2011
PubMed
まとめ

4-ヒドロキシフェニルアセテートデカルボキシラーゼに関する構造的な洞察は,クロストリジウム・ディフィシル菌の毒性の要因であるp-クレソール形成のための新しいメカニズムを明らかにします. このグリシル基の酵素は,チロシン発酵のためにユニークな基板結合モードを使用します.

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