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Updated: May 30, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
11:56

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection

Published on: October 25, 2013

二重D-Ala-D-alaとD-Ala-D-Lac結合のために設計された再設計されたバンコマイシンは,バンコマイシン耐性細菌に対する強力な抗菌活性を示しています

Jian Xie1, Joshua G Pierce, Robert C James

  • 1Department of Chemistry, The Skaggs Institute for Chemical Biology, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|August 10, 2011
PubMed
まとめ

新型バンコマイシン誘導体である[Ψ[C[NH]NH]Tpg[4]バンコマイシンアグリコンは,d-Ala-d-Alaとd-Ala-d-Lacの標的の両方に結合することによって,バンコマイシン耐性細菌に対する抗菌活性を再生します.

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