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Updated: May 30, 2026
08:17
Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
左心室ダイアストリック機能障害の進行と心不全のリスク
Garvan C Kane1, Barry L Karon, Douglas W Mahoney
1Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
JAMA
|August 25, 2011
まとめ
一般的な心臓問題であるダイアストリック機能障害は,年齢とともに増加します. この状態は,時間の経過とともに心不全を発症するリスクを大幅に高めます.
科学分野:
- 心臓病学 心臓病学
- ゲリアトリクス ゲリアトリクス
- 公衆衛生は公衆衛生である.
背景:
- 心不全の発生率は年齢とともに増加し,多くの症例では左心室のエジェクション分子が保存されている.
- 浸透性機能不全は,発射分子が保たれた心不全に関連しているが,社会における年齢による変化は十分に理解されていない.
研究 の 目的:
- ダイアストリック機能の長時間変化を追跡する.
- ディアストリック機能不全と心不全のリスクとの関連性を評価する.
主な方法:
- 45歳以上の2042人の成人を対象とした人口ベースのコホート (オルムステッド郡心臓機能研究) が,エコーカルディオグラフィーを受けた.
- ディアストロリック機能は,ベースラインと4年後に (正常から重症) グレード化されました.
- インシデント心不全のフォローアップは,約6年間行われました.
主要な成果:
- ディアストリック機能障害の罹患率は4年間で23.8%から39.2%に増加し,機能の悪化は65歳以上の人ではより一般的であった.
- ダイアストリック機能不全の悪化は,心不全のリスクの増加と関連していた (リスク比1.81).
- 心不全のリスクは,静脈動脈機能不全の重症度とともに上昇した.
結論:
- ディアストリック機能不全の罹患率は,人口ベースのコホートで4年間にわたって有意に増加しました.
- 立方体機能不全は,一般人における心不全の有意な予測因子である.
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