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Updated: May 4, 2026

In Vitro Polymerization of F-actin on Early Endosomes
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尾に固定されたタンパク質挿入における膜関連ステップのメカニズム

Malaiyalam Mariappan1, Agnieszka Mateja, Malgorzata Dobosz

  • 1Cell Biology and Metabolism Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|August 26, 2011
PubMed
まとめ

この研究では,エンドプラズマの網膜に尾を固定した (TA) タンパク質の挿入のメカニズムを明らかにしています. 研究者は,精製された成分を用いてサイクルを再構成し,Get3チャペロン複合体が,Get1とGet2の相互作用を通じてTAタンパク質を標的にして挿入する方法を明らかにしました.

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