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Updated: May 29, 2026

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins
05:35

Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins

Published on: March 3, 2016

定義されたクロマチンのテンプレート上で,センターメアとキネトコアをインビトロ組み立てます

Annika Guse1, Christopher W Carroll, Ben Moree

  • 1Department of Biochemistry, Stanford Medical School, Beckman 409A, Stanford, California 94305-5307, USA.

Nature
|August 30, 2011
PubMed
まとめ

研究者は,細胞分裂におけるその役割を研究するために,合成セントロメアタンパク質A (CENP-A) クロマチンを作成しました. 彼らは,CENP-Aのカルボキシ終端がキネトコア組立と機能の鍵であり,それをターゲットドメインから分離することを発見しました.

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