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Updated: May 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

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染色体16p11.2の位置における遺伝子用量に関連した,極端なBMIのフェノタイプをミラーリングする

Sébastien Jacquemont1, Alexandre Reymond, Flore Zufferey

  • 1Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.

Nature
|September 2, 2011
PubMed
まとめ

染色体16の遺伝的重複は,減量に関連した肥満と対照的に,体重不足に関連しています. この発見は,肥満と体重不足の遺伝的原因を反映し,エネルギーバランスに影響を与えることを示唆しています.

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