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Updated: May 29, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

合理的ドメインスワップは,キノコのポリケチド合成酵素のプログラムを解読し,絶滅した代謝物質を復活させる

Katja M Fisch1, Walid Bakeer, Ahmed A Yakasai

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.

Journal of the American Chemical Society
|September 9, 2011
PubMed
まとめ

繰り返しポリケチド合成酵素 (PKS) のプログラミングを理解することは極めて重要です. PKSにおけるドメインスワップは,プログラミングの起源を明らかにし,絶滅した代謝産物であるベースアニニンの復活を可能にしました.

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