心臓病は,外周深静脈栓塞がなければ肺栓塞の危険因子である可能性があります
Henrik T Sørensen1, Erzsebet Horvath-Puho, Timothy L Lash
1Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Allé 43-45, DK-8200 Aarhus N, Denmark. hts@dce.au.dk
Circulation
|September 9, 2011
まとめ
心臓病は,同時に深静脈栓塞 (DVT) を伴わない肺栓塞 (PE) のリスクを大幅に高めます. この研究は,前述の心臓発作と単離のPEとの強い関連性を確認し,重要な臨床的考慮事項を強調しています.
科学分野:
- 心臓病学 心臓病学
- 血管医学 血管医学とは
- エピデミオロジー エピデミオロジー
背景:
- 心臓病は,動脈栓塞の危険因子として知られています.
- 心臓病と肺栓塞 (PE) の関連性は,特に周周周静脈血栓症 (PVT) がなければ,さらに明確にする必要があります.
研究 の 目的:
- 前発性心疾患と肺栓塞,特に単発性PEのリスクとの関係を調査する.
- 心臓病歴のある患者のPEおよび深静脈血栓症 (DVT) のリスクを定量化するために.
主な方法:
- デンマークでは,全国規模で,人口を対象とした症例対照研究が行われました.
- 1980年から2007年のデータには,PEおよび/またはDVTと診断された患者と,集団コントロールを含む.
- 確率比は,異なる静脈性血栓塞栓症のアウトカムで,心臓病に先行する相対的なリスクを評価するために計算されました.
主要な成果:
- 前3ヶ月間の心筋梗塞および心不全は,単発性PEのリスクを有意に増加させました (それぞれOR 43.5と32.4).
- PEとDVTの組み合わせ,およびDVT単独のリスクは,単一のPEと比較して低かった.
- 右側弁疾患は,左側疾患 (13.5) よりもPE (74.6) の確率比がかなり高かった.
結論:
- 心臓病は,肺栓塞の短期的リスクを大幅に高めます.
- 診断された外周静脈血栓症なしで発生するPEの場合は特にリスクが高まります.
関連する概念動画
Peripheral Artery Disease I: Introduction
663
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
663
Venous Thrombosis I: Introduction
831
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
831
Pulmonary Embolism I: Introduction
1.5K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.5K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
760
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
760
Pulmonary Embolism III: Nursing Management
756
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
756
Pulmonary Embolism I: Introduction
65
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
65


