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Updated: May 29, 2026

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
08:23

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats

Published on: March 13, 2012

HCN2イオンチャネルは,炎症性および神経疾患性疼痛において中心的な役割を果たします

Edward C Emery1, Gareth T Young, Esther M Berrocoso

  • 1Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.

Science (New York, N.Y.)
|September 10, 2011
PubMed
まとめ

HCN2イオンチャネルは,ノシセプターのアクションポテンシャル発射を駆動することにより,神経疾患の痛みを誘発するのに不可欠です. 特定の痛みを感知するニューロンのHCN2を削除すると,神経損傷後の神経疾患の痛みの発生を防ぐことができます.

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